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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNFRSF1A
All Species:
8.79
Human Site:
S251
Identified Species:
21.48
UniProt:
P19438
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19438
NP_001056.1
455
50495
S251
Y
S
I
V
C
G
K
S
T
P
E
K
E
G
E
Chimpanzee
Pan troglodytes
XP_522334
496
54662
K294
K
W
E
D
S
A
H
K
P
Q
S
L
D
T
D
Rhesus Macaque
Macaca mulatta
XP_001118232
453
50420
S249
Y
A
I
V
C
G
K
S
T
P
E
K
E
G
E
Dog
Lupus familis
XP_854474
452
49936
T251
S
I
V
C
G
K
P
T
P
T
K
E
G
E
P
Cat
Felis silvestris
Mouse
Mus musculus
P25118
454
50111
D251
V
Y
S
I
I
C
R
D
P
V
P
V
K
E
E
Rat
Rattus norvegicus
P22934
461
50951
S251
Y
S
I
I
C
R
D
S
A
P
V
K
E
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507193
387
42412
P218
Y
C
Y
W
K
R
R
P
P
Q
S
S
S
R
G
Chicken
Gallus gallus
NP_001025950
427
47701
G254
V
K
L
V
Q
K
N
G
I
A
S
S
F
Y
S
Frog
Xenopus laevis
NP_001108251
412
46384
F243
C
L
A
G
V
T
L
F
I
V
R
S
N
L
K
Zebra Danio
Brachydanio rerio
NP_998355
389
44081
A220
S
I
M
V
L
S
L
A
I
F
M
A
Y
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52
94.2
74
N.A.
64.6
64.2
N.A.
25.4
34
33.4
23.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
57.2
96.6
81.3
N.A.
74.9
74.4
N.A.
37.1
52.9
49.4
41
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
93.3
0
N.A.
6.6
60
N.A.
6.6
6.6
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
26.6
N.A.
26.6
66.6
N.A.
13.3
13.3
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
10
0
10
10
10
0
10
0
0
0
% A
% Cys:
10
10
0
10
30
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
10
10
0
0
0
0
10
0
10
% D
% Glu:
0
0
10
0
0
0
0
0
0
0
20
10
30
30
40
% E
% Phe:
0
0
0
0
0
0
0
10
0
10
0
0
10
0
0
% F
% Gly:
0
0
0
10
10
20
0
10
0
0
0
0
10
20
20
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
20
30
20
10
0
0
0
30
0
0
0
0
0
0
% I
% Lys:
10
10
0
0
10
20
20
10
0
0
10
30
10
0
10
% K
% Leu:
0
10
10
0
10
0
20
0
0
0
0
10
0
10
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
10
10
40
30
10
0
0
0
10
% P
% Gln:
0
0
0
0
10
0
0
0
0
20
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
20
20
0
0
0
10
0
0
10
0
% R
% Ser:
20
20
10
0
10
10
0
30
0
0
30
30
10
0
10
% S
% Thr:
0
0
0
0
0
10
0
10
20
10
0
0
0
10
0
% T
% Val:
20
0
10
40
10
0
0
0
0
20
10
10
0
10
0
% V
% Trp:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
40
10
10
0
0
0
0
0
0
0
0
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _